Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | DNA2 | P51530 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MDH2 | P40926 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522706 | 0.73 | KDM4E (0.39) | CSNK2A1CSNK2A2CSNK2BKDM4EHPGD | |
| SCHEMBL11025809 | 0.69 | MAPKAPK3 (0.45) | CSNK2A1ALDH1A1PIM1CDK2FLT4 | |
| SCHEMBL11022445 | 0.69 | KDM4E (0.55) | KDM4EHPGDALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL10867508 | 0.68 | ALDH1A1 (0.47) | CSNK2A1CSNK2A2CSNK2BKDM4EHPGD | |
| SCHEMBL10867795 | 0.67 | KDM4E (0.36) | CSNK2A1CSNK2A2CSNK2BKDM4EHPGD | |
| Water SCHEMBL29402051 | 0.67 | CSNK2A2 (0.45) | CSNK2A1CSNK2A2CSNK2BKDM4EHPGD | |
| SCHEMBL11116041 | 0.67 | KDM4E (0.40) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL10768051 | 0.66 | KDM4E (0.43) | CSNK2A1CSNK2A2CSNK2BKDM4EHPGD | |
| SCHEMBL10755284 | 0.66 | KCNH2 (0.42) | KDM4EHPGDALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL10753255 | 0.65 | ALDH1A1 (0.41) | KDM4EHPGDALDH1A1HSD17B10PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571400-A1 | NOVEL QUINOLONE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO.,LTD. (KR) | 1993-12-01 | — | — | EP | disclosed |