Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274366 | 1.00 | MEN1 (0.47) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL8563248 | 0.86 | HTT (0.65) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL54411 | 0.85 | TSHR (0.50) | MEN1KMT2ASMN1; SMN2HPGDAPOBEC3G | |
| SCHEMBL8539706 | 0.85 | TSHR (0.50) | MEN1KMT2ASMN1; SMN2HPGDAPOBEC3G | |
| SCHEMBL134242 | 0.76 | KMT2A (0.73) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL9706943 | 0.76 | KMT2A (0.73) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL29462402 | 0.76 | KMT2A (0.73) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| Dalapon SCHEMBL9674076 | 0.75 | KMT2A (0.60) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| Dalapon SCHEMBL22444532 | 0.75 | KMT2A (0.60) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL8563911 | 0.74 | RAB9A (0.74) | MEN1KMT2AHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523067-A1 | CROP-SELECTIVE HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-20 | — | — | EP | disclosed |