Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193841 | 0.85 | CRHR1 (0.39) | EGFRCRHR1RPS6KB1AKT1 | |
| SCHEMBL9869337 | 0.83 | TDP1 (0.38) | EGFRACACBGPR88CRHR1SLC2A1 | |
| SCHEMBL9523756 | 0.81 | CRHR1 (0.39) | EGFRACACBCRHR1RPS6KB1AKT1 | |
| SCHEMBL9084666 | 0.80 | PTGER4 (0.40) | EGFRCRHR1RPS6KB1 | |
| SCHEMBL9216328 | 0.80 | AURKA (0.42) | EGFRCRHR1RPS6KB1AKT1 | |
| SCHEMBL9524682 | 0.79 | EGFR (0.36) | EGFRACACBCRHR1RPS6KB1SLC2A1 | |
| SCHEMBL9775791 | 0.79 | EGFR (0.36) | EGFRACACBCRHR1RPS6KB1AKT1 | |
| SCHEMBL9215501 | 0.79 | EGFR (0.36) | EGFRCRHR1RPS6KB1AKT1 | |
| SCHEMBL9523823 | 0.79 | CRHR1 (0.42) | EGFRCRHR1RPS6KB1AKT1 | |
| SCHEMBL9836762 | 0.79 | EGFR (0.36) | EGFRACACBCRHR1RPS6KB1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985426-A | AGRICULTURAL USE | UBE INDUSTRIES, LTD. (JP) | 1991-01-15 | — | — | US | claimed |
| EP-0264217-B1 | ARALKYLAMINOPYRIMIDINE DERIVATIVE, PROCESS FOR PRODUCING THEREOF AND INSECTICIDE, ACARICIDE AND FUNGICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | UBE INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4985426-A | AGRICULTURAL USE | UBE INDUSTRIES, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4895849-A | Aralkylaminopyrimidine compounds which are useful as for producing thereof and insecticides | UBE INDUSTRIES, LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0264217-A2 | Aralkylaminopyrimidine derivative, process for producing thereof and insecticide, acaricide and fungicide containing said derivative as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1988-04-20 | — | — | EP | disclosed |