SCHEMBL9524334

SCHEMBL9524334

O=C(COc1ccc(Cl)cc1)NNCl

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATF4 P18848 4/20 0.61
NPSR1 Q6W5P4 1/20 0.59
KMT2A Q03164 4/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
MEN1 O00255 3/20 0.58
ALDH1A1 P00352 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SENP2 Q9HC62 1/20 0.58
SENP1 Q9P0U3 1/20 0.58
TSHR P16473 1/20 0.58
KDM4E B2RXH2 1/20 0.57
ADAMTS5 Q9UNA0 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12693872 0.85 KMT2A (0.61) ATF4NPSR1KMT2ANPC1RAB9A
SCHEMBL29138719 0.84 KMT2A (0.60) ATF4NPSR1KMT2ANPC1RAB9A
SCHEMBL1255820 0.83 ATF4 (0.63) ATF4NPSR1KMT2AMEN1ALDH1A1
SCHEMBL28104179 0.83 KMT2A (0.66) NPSR1KMT2ANPC1RAB9AMEN1
SCHEMBL7492782 0.81 KMT2A (0.62) ATF4NPSR1KMT2ANPC1RAB9A
SCHEMBL11547674 0.81 ALDH1A1 (0.63) ATF4NPSR1KMT2ANPC1RAB9A
SCHEMBL2610071 0.80 MEN1 (0.85) NPSR1KMT2ANPC1RAB9AMEN1
Hydrochloric Acid SCHEMBL27734857 0.80 KMT2A (0.60) ATF4NPSR1KMT2ANPC1RAB9A
SCHEMBL16082990 0.80 MEN1 (0.85) NPSR1KMT2ANPC1RAB9AMEN1
Iproclozide SCHEMBL49744 0.80 KMT2A (0.56) ATF4NPSR1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0396769-B1 AZOXY COMPOUND KOWA CO. LTD. (JP) 1993-03-10 EP disclosed
US-5093480-A Fungicides KOWA COMPANY, LTD. (JP) 1992-03-03 US disclosed