Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | F2R | P25116 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524419 | 0.86 | HTT (0.39) | TP53HTTRORCALDH1A1SMN1; SMN2 | |
| SCHEMBL7853959 | 0.81 | TP53 (0.42) | TP53F2RRORCALDH1A1ESR1 | |
| SCHEMBL10441682 | 0.76 | ALDH1A1 (0.40) | HTTALDH1A1NPSR1AKR1B1 | |
| SCHEMBL6131273 | 0.73 | TP53 (0.62) | TP53HTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL28606757 | 0.72 | ESR1 (0.47) | ALDH1A1ESR1NPSR1 | |
| SCHEMBL28610868 | 0.71 | PARP10 (0.50) | TP53HTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10710269 | 0.71 | TP53 (0.66) | TP53HTTALDH1A1NR1I2NPSR1 | |
| SCHEMBL3138343 | 0.70 | SIGMAR1 (0.45) | TP53HTTALDH1A1NPSR1 | |
| SCHEMBL22671301 | 0.69 | TP53 (0.45) | TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL19494060 | 0.68 | FEN1 (0.53) | HTTF2RALDH1A1SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396769-B1 | AZOXY COMPOUND | KOWA CO. LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5093480-A | Fungicides | KOWA COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0396769-A1 | AZOXY COMPOUND | KOWA CO. LTD. (JP) | 1990-11-14 | — | — | EP | disclosed |