Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524378 | 0.86 | TP53 (0.41) | HTTALDH1A1AKR1B1SMN1; SMN2RORC | |
| SCHEMBL17513526 | 0.81 | ALDH1A1 (0.40) | HTTOPRM1ALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL10441682 | 0.79 | ALDH1A1 (0.40) | HTTALDH1A1AKR1B1CYP2D6CYP3A4 | |
| SCHEMBL24747408 | 0.74 | ALDH1A1 (0.38) | HTTOPRM1ALDH1A1AKR1B1CYP1A2 | |
| SCHEMBL28610868 | 0.74 | PARP10 (0.50) | HTTALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28606757 | 0.72 | ESR1 (0.47) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL3388559 | 0.71 | ALDH1A1 (0.48) | HTTOPRM1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL28612064 | 0.70 | NPC1 (0.44) | HTTALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23723677 | 0.68 | HTT (0.44) | HTTALDH1A1AKR1B1CYP3A4SMN1; SMN2 | |
| 1,2-Dichlorobenzene SCHEMBL27647229 | 0.67 | LMNA (0.48) | ALDH1A1CYP2D6CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396769-B1 | AZOXY COMPOUND | KOWA CO. LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5093480-A | Fungicides | KOWA COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0396769-A1 | AZOXY COMPOUND | KOWA CO. LTD. (JP) | 1990-11-14 | — | — | EP | disclosed |