Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526774 | 0.78 | PDPK1 (0.51) | DRD1 | |
| SCHEMBL9525557 | 0.77 | MAPK1 (0.51) | ATMDRD1 | |
| SCHEMBL10388437 | 0.77 | DRD1 (0.47) | DRD1 | |
| SCHEMBL7491666 | 0.76 | CYP19A1 (0.49) | DRD1 | |
| SCHEMBL16168685 | 0.75 | MEN1 (0.53) | DRD1 | |
| SCHEMBL7774816 | 0.75 | DRD1 (0.49) | DRD1 | |
| SCHEMBL540767 | 0.75 | MAPK1 (0.67) | ALDH1A1ATMHSD17B10DRD1 | |
| SCHEMBL9524857 | 0.74 | RPS6KA5 (0.61) | DRD1 | |
| SCHEMBL9867733 | 0.73 | RXRA (0.45) | — | |
| SCHEMBL9524646 | 0.72 | TP53 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |