Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.45 |
| ▸ | TCF7L2 | Q9NQB0 | 6/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524278 | 0.90 | SNCA (0.47) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9525587 | 0.87 | ADORA3 (0.47) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL9524788 | 0.87 | KCNK3 (0.49) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9525125 | 0.85 | MAPT (0.50) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9524408 | 0.85 | P2RX1 (0.53) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9525537 | 0.84 | KCNK3 (0.49) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9525813 | 0.84 | MEN1 (0.50) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9524293 | 0.82 | TP53 (0.46) | RAB9ANPC1SMN1; SMN2POLBHPGD | |
| SCHEMBL9525863 | 0.82 | RAB9A (0.49) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9525673 | 0.80 | MAOB (0.50) | RAB9ANPC1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |