Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524888 | 0.91 | MEN1 (0.49) | KCNK3KCNK9RAB9ANPC1ALDH1A1 | |
| SCHEMBL9524620 | 0.90 | P2RX1 (0.52) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL9525587 | 0.87 | ADORA3 (0.47) | MAOBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9524788 | 0.86 | KCNK3 (0.49) | KCNK3KCNK9RAB9ANPC1ALDH1A1 | |
| SCHEMBL9525519 | 0.86 | FADS1 (0.52) | RAB9ANPC1MEN1KMT2AHIF1A | |
| SCHEMBL9524250 | 0.85 | HIF1A (0.58) | MAOBKCNK3KCNK9RAB9ANPC1 | |
| SCHEMBL9524507 | 0.85 | P2RX1 (0.50) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL9524693 | 0.85 | FADS1 (0.58) | MAOBRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL9525061 | 0.82 | RAB9A (0.51) | RAB9ANPC1MEN1KMT2AHIF1A | |
| SCHEMBL9524344 | 0.82 | TMPRSS4 (0.51) | RAB9ANPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |