Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | CALCA | P06881 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523824 | 0.86 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2PTGER4MAPTCYP1A2 | |
| SCHEMBL9527944 | 0.86 | NSD2 (0.50) | ALDH1A1ADORA2AMAPTKMT2A | |
| SCHEMBL9525718 | 0.85 | TP53 (0.47) | ADORA2AADORA1PTGER4CYP1A2CYP2C19 | |
| SCHEMBL9524520 | 0.85 | LMNA (0.51) | ALDH1A1SMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL9524438 | 0.85 | MEN1 (0.50) | ADORA2AADORA1CYP2C19KMT2AADORA3 | |
| SCHEMBL9523879 | 0.82 | GSK3B (0.53) | SMN1; SMN2PTGER4MAPTKMT2A | |
| SCHEMBL9527272 | 0.81 | PTPN1 (0.50) | ALDH1A1SMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL9525598 | 0.81 | KMT2A (0.49) | ALDH1A1MAPTCYP2C19KMT2A | |
| SCHEMBL9524293 | 0.81 | TP53 (0.46) | SMN1; SMN2KMT2AADORA3RAB9A | |
| SCHEMBL9524845 | 0.80 | PLA2G2A (0.41) | ALDH1A1PTGER4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | claimed |
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |