SCHEMBL9524845

SCHEMBL9524845

O=C(NCc1ccccc1)Oc1nnc2ccc(F)cc2c1O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.41
ALDH1A1 P00352 2/20 0.40
RAB9A P51151 1/20 0.40
NCEH1 Q6PIU2 1/20 0.40
MGLL Q99685 1/20 0.39
EPHX1 P07099 1/20 0.39
PTGER4 P35408 1/20 0.39
CHRM4 P08173 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9524931 0.87 FAAH (0.44) ALDH1A1RAB9APTGER4
SCHEMBL9524448 0.87 NCEH1 (0.46) RAB9ANCEH1MGLLEPHX1
SCHEMBL9525182 0.86 GABRP (0.42) PLA2G2ANCEH1
SCHEMBL9527439 0.86 SMN1; SMN2 (0.43) RAB9ANCEH1MGLLEPHX1
SCHEMBL9524784 0.84 TACR3 (0.46) PLA2G2AALDH1A1RAB9A
SCHEMBL9524870 0.82 CSF1R (0.45) ALDH1A1RAB9A
SCHEMBL9524641 0.80 ALDH1A1 (0.45) ALDH1A1RAB9APTGER4
SCHEMBL9525091 0.77 RAB9A (0.41) ALDH1A1RAB9A
SCHEMBL9524715 0.77 MEN1 (0.43) RAB9A
SCHEMBL9525669 0.76 NPC1 (0.44) RAB9ACHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277791-B1 CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION FARMITALIA CARLO ERBA S.r.l. (IT) 1993-06-02 EP claimed