Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLR1A | O95602 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523583 | 0.91 | KDM4E (0.52) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9525554 | 0.89 | KDM4E (0.54) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9525651 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EHPGDMEN1KMT2A | |
| SCHEMBL9524962 | 0.78 | CACNA1B (0.51) | POLR1A | |
| SCHEMBL9527401 | 0.78 | TSHR (0.51) | USP2HDAC2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9524590 | 0.77 | RAD52 (0.49) | SMN1; SMN2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL6956940 | 0.76 | HTR1A (0.66) | SMN1; SMN2KDM4EALDH1A1DRD2 | |
| SCHEMBL9525682 | 0.76 | NAAA (0.52) | USP2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL9525892 | 0.76 | NAAA (0.52) | USP2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL9523732 | 0.75 | RAB9A (0.55) | HDAC2HDAC8HDAC6SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |