Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 5/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521262 | 0.79 | FPR2 (0.34) | F2RL1FPR2WRNADRA2AADRA2C | |
| SCHEMBL5353787 | 0.72 | ALDH1A1 (0.43) | SMN1; SMN2F2RL1FPR2ADRA2AADRA2C | |
| SCHEMBL9522500 | 0.70 | AHR (0.41) | TP53MAPTF2RL1ADRA2AADRA2C | |
| SCHEMBL2051189 | 0.69 | NISCH (0.42) | MAPTTAAR1ADRA2AADRA2CNISCH | |
| SCHEMBL1348889 | 0.64 | SLC6A2 (0.50) | F2RL1TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL947712 | 0.64 | — | — | |
| SCHEMBL31629220 | 0.62 | F2RL1 (0.42) | F2RL1NISCH | |
| SCHEMBL8078116 | 0.62 | — | — | |
| SCHEMBL3170537 | 0.62 | NISCH (0.53) | SMN1; SMN2F2RL1FPR2ADRA2AADRA2C | |
| SCHEMBL10642682 | 0.62 | F2RL1 (0.42) | F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573529-A1 | TRIHETEROARYLMETHANES, METHOD FOR PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE TO MANUFACTURE DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992015578-A1 | TRIHETEROARYLMETHANES, METHOD FOR PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE TO MANUFACTURE DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-09-17 | — | — | WO | disclosed |