Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 2/20 | 0.33 |
| ▸ | SCN4A | P35499 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865738 | 0.80 | SLC6A2 (0.45) | DPP4F2CYP19A1 | |
| SCHEMBL7921340 | 0.78 | CYP19A1 (0.32) | DPP4F2AKT2CYP19A1 | |
| SCHEMBL1281771 | 0.77 | SMN1; SMN2 (0.40) | LMNA | |
| SCHEMBL11351479 | 0.77 | TSHR (0.38) | CYP19A1 | |
| SCHEMBL15437001 | 0.77 | HTR2C (0.42) | ADRA2AADRA2CLMNAHIF1ACYP19A1 | |
| SCHEMBL11344228 | 0.77 | CES2 (0.32) | CYP19A1 | |
| Water SCHEMBL1982282 | 0.76 | SMN1; SMN2 (0.39) | LMNA | |
| SCHEMBL2686848 | 0.74 | HTR2A (0.31) | — | |
| SCHEMBL9634376 | 0.74 | L3MBTL1 (0.35) | AKT2 | |
| SCHEMBL10560913 | 0.73 | CYP2D6 (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384734-B | Trinitrogenazole alcohol antifungal compound and the preparation method and application thereof with the side chain of oxadiazoles containing piperidines | 中国人民解放军第二军医大学 | 2018-07-17 | — | — | CN | disclosed |
| CN-105384734-A | Triazole alcohol antifungal compound with piperidine oxadiazole side chain and preparation method for compound and application of compound | UNIV PLA 2ND MILITARY MEDICAL | 2016-03-09 | — | — | CN | disclosed |
| CN-104356125-A | Triazole alcohol antifungal compound with side chain containing piperidine oxadiazole as well as preparation method and application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2015-02-18 | — | — | CN | disclosed |
| CN-102311399-A | Triazole alcohol antifungal compounds with nitrogen-containing side chains, preparation method thereof and application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2012-01-11 | — | — | CN | disclosed |
| CN-1303073-C | Substituted triazolone benzyl amine triazole antifungal compounds and method for preparing same | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2007-03-07 | — | — | CN | disclosed |
| CN-1303073-C | Substituted triazolone benzyl amine triazole antifungal compounds and method for preparing same | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2007-03-07 | — | — | CN | disclosed |
| CN-1699351-A | Substituted triazolone benzyl amine triazole antifungal compounds and method for preparing same | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2005-11-23 | — | — | CN | disclosed |
| CN-1699351-A | Substituted triazolone benzyl amine triazole antifungal compounds and method for preparing same | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2005-11-23 | — | — | CN | disclosed |
| CN-1699351-A | Substituted triazolone benzyl amine triazole antifungal compounds and method for preparing same | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2005-11-23 | — | — | CN | disclosed |
| EP-0515546-A4 | TRIAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | — | 1993-05-12 | — | — | EP | disclosed |
| EP-0515546-A1 | TRIAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |