Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114332 | 0.89 | KDM4E (0.58) | KDM4EMAPTALDH1A1KMT2AGAA | |
| SCHEMBL5162466 | 0.86 | POLB (0.44) | KDM4EALDH1A1KMT2AGAAGLA | |
| SCHEMBL12000685 | 0.86 | ALDH1A1 (0.51) | KDM4EMAPTALDH1A1KMT2AGAA | |
| SCHEMBL3859668 | 0.86 | TUBB4A (0.57) | ALDH1A1KMT2AGAAMEN1CYP1A2 | |
| SCHEMBL29358077 | 0.84 | GAA (0.47) | KDM4EMAPTALDH1A1KMT2AGAA | |
| SCHEMBL12444463 | 0.84 | L3MBTL1 (0.50) | KDM4EMAPTALDH1A1KMT2AGAA | |
| SCHEMBL22537442 | 0.84 | ALDH1A1 (0.43) | KDM4EMAPTALDH1A1KMT2AGAA | |
| SCHEMBL36033 | 0.84 | GAA (0.47) | KDM4EMAPTALDH1A1KMT2AGAA | |
| SCHEMBL4534380 | 0.84 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1KMT2AGAA | |
| SCHEMBL3821707 | 0.83 | MAPT (0.53) | KDM4EMAPTALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |
| CN-85103112-B | Oxidation hair dye based on low viscosity carrier material | 威娜股份有限公司 | 1988-09-28 | — | — | CN | disclosed |
| CN-85103112-A | Oxide hair dye based on the low viscosity carrier material | — | 1986-10-22 | — | — | CN | disclosed |