Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312983 | 0.90 | ALDH1A1 (0.69) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL30021051 | 0.88 | TDP1 (0.61) | ALDH1A1POLBCASP2SMN1; SMN2LMNA | |
| SCHEMBL1494291 | 0.84 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL1494383 | 0.84 | ALDH1A1 (0.56) | ALDH1A1POLBCASP2SMN1; SMN2LMNA | |
| SCHEMBL17536233 | 0.84 | ALDH1A1 (0.67) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL9312894 | 0.84 | ALDH1A1 (0.62) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL30022962 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL7035785 | 0.82 | HSD17B1 (0.56) | ALDH1A1CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL8802148 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL31554478 | 0.81 | HPGD (0.56) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523046-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA 2? AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5159085-A | Antiinflammatory, antiallergens, cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-5021576-A | Antiinflammatory, antiarthritic, hypotensive, anticarcinogenic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| WO-1991006539-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-16 | — | — | WO | disclosed |