Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795476 | 0.87 | KDM4E (0.55) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL22060302 | 0.81 | KCNA5 (0.53) | LMNASMN1; SMN2CYP1A2HIF1AKCNA5 | |
| SCHEMBL16477945 | 0.81 | KCNA5 (0.53) | LMNASMN1; SMN2CYP1A2HIF1AKCNA5 | |
| SCHEMBL1156021 | 0.81 | KCNA5 (0.53) | LMNASMN1; SMN2CYP1A2HIF1AKCNA5 | |
| SCHEMBL20034107 | 0.81 | KCNA5 (0.53) | LMNASMN1; SMN2CYP1A2HIF1AKCNA5 | |
| SCHEMBL13883296 | 0.80 | KDM4E (0.63) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL16976538 | 0.77 | KDM4E (0.59) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL13484333 | 0.76 | FAAH (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL21715702 | 0.73 | HTR1A (0.35) | TP53KCNH2 | |
| SCHEMBL18158031 | 0.73 | KDM4E (0.63) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227162-B1 | COMPLEX-FORMING POLYMERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-09-22 | — | — | EP | disclosed |
| EP-0227162-A2 | Complex-forming polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-07-01 | — | — | EP | disclosed |