Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744436 | 0.86 | TSHR (0.42) | FAAHHTTKDM4ELMNACCR1 | |
| SCHEMBL13484328 | 0.82 | TSHR (0.46) | FAAHHTTKDM4ELMNACCR1 | |
| SCHEMBL9525347 | 0.76 | KDM4E (0.52) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL13848520 | 0.74 | FAAH (0.45) | FAAHHTTKDM4ELMNACCR1 | |
| SCHEMBL13484330 | 0.73 | FAAH (0.46) | FAAHCES1 | |
| SCHEMBL13484335 | 0.73 | SLC6A3 (0.34) | KDM4ELMNATSHRALOX15SMN1; SMN2 | |
| SCHEMBL13484313 | 0.73 | KDM4E (0.48) | FAAHHTTKDM4ELMNACCR1 | |
| SCHEMBL23791344 | 0.71 | CA12 (0.31) | — | |
| SCHEMBL13484018 | 0.71 | KDM4E (0.54) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL13484363 | 0.71 | CYP2D6 (0.36) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662971-B2 | enzyme inhibitor for treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |