Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 15/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525542 | 0.87 | KMT2A (0.64) | AMY1AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9525818 | 0.82 | MEN1 (0.55) | AMY1AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11244851 | 0.80 | AMY1A (0.59) | AMY1AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9526187 | 0.79 | AMY1A (0.57) | AMY1AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9524224 | 0.78 | KMT2A (0.60) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9524221 | 0.78 | KMT2A (0.60) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9524479 | 0.77 | KDM4E (0.62) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9524488 | 0.77 | KDM4E (0.62) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6951498 | 0.76 | L3MBTL1 (0.54) | AMY1AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6951495 | 0.76 | L3MBTL1 (0.54) | AMY1AMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028717-A | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| US-4909827-A | Containing a C6-10 aryl group substituted in position 1 | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| EP-0274642-A2 | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AG (DE) | 1988-07-20 | — | — | EP | disclosed |