Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 5/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 4/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526834 | 0.92 | FFAR1 (0.39) | FFAR1FFAR4EDNRAEDNRB | |
| SCHEMBL9526402 | 0.82 | ADRB2 (0.39) | EDNRAEDNRB | |
| SCHEMBL9525332 | 0.82 | AGTR2 (0.38) | METAP2 | |
| SCHEMBL9526466 | 0.79 | — | — | |
| SCHEMBL9527525 | 0.79 | AGTR1 (0.38) | — | |
| SCHEMBL9525968 | 0.78 | FFAR1 (0.39) | FFAR1FFAR4 | |
| SCHEMBL9527711 | 0.77 | PPARG (0.33) | — | |
| SCHEMBL9529965 | 0.76 | AGTR1 (0.40) | — | |
| SCHEMBL9527727 | 0.75 | AGTR2 (0.41) | — | |
| SCHEMBL9530326 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523141-A4 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0523141-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | disclosed |