Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527984 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9525116 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9524204 | 0.86 | ADRA2C (0.52) | SMN1; SMN2POLBADRA2CNPC1RAB9A | |
| SCHEMBL9524919 | 0.84 | HTT (0.51) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9526274 | 0.83 | NPC1 (0.40) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9525706 | 0.83 | CYP1A2 (0.41) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9525433 | 0.81 | EPHX1 (0.45) | SMN1; SMN2POLBNPC1ALDH1A1KDM4E | |
| SCHEMBL9524354 | 0.80 | NPC1 (0.44) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9524791 | 0.80 | NPC1 (0.49) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9407533 | 0.79 | NPC1 (0.46) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |