Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525706 | 0.93 | CYP1A2 (0.41) | EPHX1SMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9528510 | 0.92 | SMN1; SMN2 (0.40) | EPHX1SMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9525362 | 0.86 | BLM (0.43) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19KDR | |
| SCHEMBL9524016 | 0.86 | ALDH1A1 (0.41) | EPHX1TRPV1KDM4EGSK3BSMN1; SMN2 | |
| SCHEMBL9524974 | 0.85 | ALDH1A1 (0.41) | TRPV1SMN1; SMN2ALDH1A1HSD17B10KDR | |
| SCHEMBL9525424 | 0.84 | ALDH1A1 (0.43) | EPHX1TRPV1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9525236 | 0.84 | ALDH1A1 (0.40) | TRPV1KDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9526588 | 0.82 | EPHX1 (0.46) | EPHX1TRPV1KDM4EGSK3BL3MBTL1 | |
| SCHEMBL9527984 | 0.81 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL9525795 | 0.81 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2ALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |