Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30460668 | 0.79 | OPRM1 (0.40) | ALOX5ADRA1DMEN1LMNAMAPT | |
| SCHEMBL8629570 | 0.77 | GAA (0.44) | GAAESR1ACP3MEN1ALDH1A1 | |
| SCHEMBL598722 | 0.77 | GAA (0.57) | GAAESR1ACP3MEN1ALDH1A1 | |
| SCHEMBL13993318 | 0.72 | ESR1 (0.59) | GAAESR1ACP3ALDH1A1 | |
| SCHEMBL30507724 | 0.70 | ESR1 (0.56) | GAAESR1ACP3ALDH1A1 | |
| Alcohol SCHEMBL598781 | 0.70 | GAA (0.50) | GAAESR1ACP3ALDH1A1LMNA | |
| SCHEMBL28973546 | 0.70 | GAA (0.65) | GAAESR1ACP3MEN1LMNA | |
| SCHEMBL3858791 | 0.70 | GAA (0.65) | GAAESR1ACP3MEN1LMNA | |
| SCHEMBL227491 | 0.70 | GAA (0.65) | GAAESR1ACP3MEN1LMNA | |
| SCHEMBL28564145 | 0.69 | ALOX5 (0.42) | GAAALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231996-B1 | NOVEL AMINO ACID DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-10-06 | — | — | EP | disclosed |
| US-4931450-A | Amino acid derivatives | NOVO INDUSTRI A/S (DK) | 1990-06-05 | — | — | US | disclosed |
| EP-0231996-A2 | Novel amino acid derivatives | NOVO NORDISK A/S (DK) | 1987-08-12 | — | — | EP | disclosed |