Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264067 | 0.84 | RAB9A (0.64) | RAB9APOLBMEN1KMT2AHPGDS | |
| SCHEMBL20402574 | 0.79 | HSD17B1 (0.46) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL9525949 | 0.78 | RAB9A (0.55) | RAB9APOLBMEN1KMT2AHPGDS | |
| SCHEMBL9613121 | 0.78 | RAB9A (0.64) | RAB9APOLBMEN1KMT2AHPGDS | |
| SCHEMBL1660905 | 0.78 | RAB9A (0.64) | RAB9APOLBMEN1KMT2AHPGDS | |
| SCHEMBL13930984 | 0.76 | HDAC6 (0.48) | RAB9APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL3756385 | 0.75 | POLB (0.70) | RAB9APOLBMEN1KMT2AHPGDS | |
| SCHEMBL10715065 | 0.74 | RAB9A (0.55) | RAB9APOLBMEN1KMT2AHPGDS | |
| SCHEMBL27782216 | 0.74 | DAO (0.61) | RAB9APOLBMEN1KMT2AHPGDS | |
| SCHEMBL422509 | 0.73 | RAB9A (0.72) | RAB9APOLBMEN1KMT2AHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259972-B1 | HETEROCYCLIC PROPENE AMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | LILLY INDUSTRIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| CN-1021050-C | PREPARING METHOD FOR BUTYRUMID DERIVATIVE | LILLY INDUSTRIES LTD (GB) | 1993-06-02 | — | — | CN | disclosed |
| US-4983619-A | Leukotriene antagonists | LILLY INDUSTRIES LIMITED (GB) | 1991-01-08 | — | — | US | disclosed |
| CN-87105515-A | Derivatives of phenylbutenamide compounds and preparation method thereof | — | 1988-03-23 | — | — | CN | disclosed |
| EP-0259972-A2 | Heterocyclic propene amide derivatives, processes for their preparation and their use as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1988-03-16 | — | — | EP | disclosed |