Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8929358 | 0.68 | CYP3A4 (0.43) | CYP3A4HPGD | |
| SCHEMBL9526227 | 0.65 | GSK3B (0.62) | CYP3A4HPGD | |
| SCHEMBL9530427 | 0.64 | — | — | |
| SCHEMBL8779762 | 0.63 | DAO (0.52) | — | |
| SCHEMBL12335749 | 0.63 | SELL (0.35) | CYP3A4HPGD | |
| SCHEMBL9925985 | 0.63 | — | — | |
| SCHEMBL7863085 | 0.63 | — | — | |
| SCHEMBL9030572 | 0.61 | MAPT (0.33) | — | |
| SCHEMBL2027674 | 0.61 | MAPT (0.47) | CYP3A4HPGD | |
| SCHEMBL12272850 | 0.60 | ALDH1A1 (0.47) | CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297697-B1 | Thiophene-2-carboxamide derivatives and their pharmaceutical use | LILLY SA (ES) | 1993-12-29 | — | — | EP | disclosed |
| EP-0297697-A1 | Thiophene-2-carboxamide derivatives and their pharmaceutical use | LILLY S.A. (ES) | 1989-01-04 | — | — | EP | disclosed |