Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.31 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | DUT | P33316 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20500252 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL20500262 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL4333525 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL4824010 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL4821411 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL20500283 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL22664469 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL38662 | 0.98 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL641418 | 0.94 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2ADH1B | |
| SCHEMBL16705774 | 0.91 | HDAC1 (0.34) | SMYD2CYP3A4HTTSMN1; SMN2LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12415770-B2 | Modulators of liver receptor homologue 1 (LRH-1) and uses | Emory University, Office of Technology Transfer (US) | 2025-09-16 | — | — | US | disclosed |
| EP-4516774-A2 | MODULATORS OF LIVER RECEPTOR HOMOLOGUE 1 (LRH-1) AND USES | Emory University (US) | 2025-03-05 | — | — | EP | disclosed |
| EP-3595652-B1 | MODULATORS OF LIVER RECEPTOR HOMOLOGUE 1 (LRH-1) | UNIV EMORY (US) | 2024-12-04 | — | — | EP | disclosed |
| US-20240368066-A1 | MODULATORS OF LIVER RECEPTOR HOMOLOGUE 1 (LRH-1) AND USES | EMORY UNIVERSITY | 2024-11-07 | — | — | US | disclosed |
| US-12065402-B2 | Modulators of liver receptor homologue 1 (LRH-1) and uses | EMORY UNIVERSITY (US) | 2024-08-20 | — | — | US | disclosed |
| US-20230295070-A1 | Modulators of Liver Receptor Homologue 1 (LRH-1) and Uses | EMORY UNIVERSITY | 2023-09-21 | — | — | US | disclosed |
| US-11691939-B2 | Modulators of liver receptor homologue 1 (LRH-1) and uses | EMORY UNIVERSITY (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210047258-A1 | Modulators of Liver Receptor Homologue 1 (LRH-1) and Uses | EMORY UNIVERSITY | 2021-02-18 | — | — | US | disclosed |
| US-10843996-B2 | Modulators of liver receptor homologue 1 (LRH-1) and uses | EMORY UNIVERSITY (US) | 2020-11-24 | — | — | US | disclosed |
| WO-2018170430-A1 | MODULATORS OF LIVER RECEPTOR HOMOLOGUE 1 (LRH-1) AND USES | EMORY UNIVERSITY (US) | 2018-09-20 | — | — | WO | disclosed |
| US-6699682-B2 | ENZYMATIC POLYPEPTIDE FOR USE IN THE TREATMENT OF SLEEP DISORDERS | THE SCRIPPS RESEARCH INSTITUTE | 2004-03-02 | — | — | US | disclosed |
| US-20020187542-A1 | Fatty-acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-12-12 | — | — | US | disclosed |
| EP-0970195-A4 | FATTY-ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6271015-B1 | A POLYPEPTIDE HAVING AN AMINO ACID SEQUENCE THAT HYDROLYSIZES CIS-9,10-OCTADECENOAMIDE AND OTHER SOPORIFIC FATTY ACID AMIDES; THERAPY FOR SLEEP DISORDERS AND NARCOLEPSY | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-07 | — | — | US | disclosed |
| EP-0833899-A4 | CIS-9,10-OCTADECENOAMIDASE | SCRIPPS RESEARCH INST (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0970195-A1 | FATTY-ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998020119-A9 | FATTY-ACID AMIDE HYDROLASE | — | 1998-11-05 | — | — | WO | disclosed |
| WO-1998020119-A1 | FATTY-ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-05-14 | — | — | WO | disclosed |
| EP-0833899-A1 | CIS-9,10-OCTADECENOAMIDASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996041869-A1 | CIS-9,10-OCTADECENOAMIDASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368066-A1 | MODULATORS OF LIVER RECEPTOR HOMOLOGUE 1 (LRH-1) AND USES | NR1H2, NR1H3, NR1H4 | SMYD2 1285/4885CYP3A4 2300/4885HTT 3051/4885 |
| US-12415770-B2 | Modulators of liver receptor homologue 1 (LRH-1) and uses | NR1H2, NR1H3, NR1H4 | SMYD2 1285/4885CYP3A4 2300/4885HTT 3051/4885 |
| US-20020187542-A1 | Fatty-acid amide hydrolase | FAAH, FAAH2, APEH | SMYD2 1000/4885CYP3A4 2355/4885HTT 4642/4885 |
| US-20230295070-A1 | Modulators of Liver Receptor Homologue 1 (LRH-1) and Uses | NR1H2, NR1H3, NR1H4 | SMYD2 1285/4885CYP3A4 2300/4885HTT 3051/4885 |
| US-11691939-B2 | Modulators of liver receptor homologue 1 (LRH-1) and uses | NR1H2, NR1H3, NR1H4 | SMYD2 1285/4885CYP3A4 2300/4885HTT 3051/4885 |
| US-12065402-B2 | Modulators of liver receptor homologue 1 (LRH-1) and uses | NR1H2, NR1H3, NR1H4 | SMYD2 1285/4885CYP3A4 2300/4885HTT 3051/4885 |
| US-10843996-B2 | Modulators of liver receptor homologue 1 (LRH-1) and uses | NR1H2, NR1H3, NR1H4 | SMYD2 1285/4885CYP3A4 2300/4885HTT 3051/4885 |
| US-20210047258-A1 | Modulators of Liver Receptor Homologue 1 (LRH-1) and Uses | NR1H2, NR1H3, NR1H4 | SMYD2 1285/4885CYP3A4 2300/4885HTT 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.