Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135579 | 0.82 | ALDH1A1 (0.70) | KDM4EALDH1A1KMT2AUSP2MEN1 | |
| SCHEMBL9525460 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1KMT2AUSP2MEN1 | |
| SCHEMBL5060064 | 0.75 | ALDH1A1 (0.63) | KDM4EALDH1A1KMT2AUSP2MEN1 | |
| SCHEMBL10345257 | 0.75 | PIM1 (0.56) | KDM4EALDH1A1KMT2AUSP2MEN1 | |
| SCHEMBL7475308 | 0.75 | ALDH1A1 (0.70) | KDM4EALDH1A1POLBHSD17B10ALOX15 | |
| SCHEMBL317705 | 0.74 | ADORA3 (0.57) | KDM4EALDH1A1KMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL10345172 | 0.74 | PIM1 (0.56) | KDM4EALDH1A1KMT2AUSP2MEN1 | |
| SCHEMBL22122723 | 0.73 | ALDH1A1 (0.57) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL314343 | 0.73 | MC4R (0.60) | KDM4EALDH1A1KMT2ALMNAHTT | |
| SCHEMBL9526456 | 0.73 | HPGD (0.47) | KDM4EALDH1A1KMT2AUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |