Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557526 | 0.80 | LMNA (0.62) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL16957293 | 0.79 | CHRM2 (0.39) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL23558619 | 0.78 | ALDH1A1 (0.48) | ALOX15LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL12518598 | 0.77 | LMNA (0.40) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL13320404 | 0.77 | SMN1; SMN2 (0.55) | ALOX15LMNATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL8733422 | 0.76 | CYP1A2 (0.53) | CHRM2LMNAL3MBTL1MAPTNPSR1 | |
| SCHEMBL13391640 | 0.75 | ALOX15 (0.40) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL1837129 | 0.75 | LMNA (0.49) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL23095838 | 0.75 | PPARG (0.46) | LMNAL3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL2043221 | 0.75 | CHRM2 (0.49) | CHRM2ALOX15LMNACHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |