Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9524291 | 0.94 | HDAC1 (0.37) | ALDH1A1HSD17B10MTNR1AMTNR1BHDAC1 | |
| Hydrochloric Acid SCHEMBL9526588 | 0.88 | EPHX1 (0.46) | ALDH1A1HSD17B10MTNR1AMTNR1BMEN1 | |
| Hydrochloric Acid SCHEMBL9528526 | 0.87 | SLC6A9 (0.38) | ALDH1A1HSD17B10MTNR1AMTNR1BHDAC6 | |
| Hydrochloric Acid SCHEMBL9524798 | 0.86 | CYP1A2 (0.40) | ALDH1A1HSD17B10MTNR1AMTNR1BHDAC1 | |
| Hydrochloric Acid SCHEMBL9525275 | 0.86 | EPHX1 (0.40) | ALDH1A1HSD17B10MTNR1AMTNR1BHDAC1 | |
| Hydrochloric Acid SCHEMBL9523921 | 0.82 | MAPT (0.37) | MEN1KMT2AHPGDMAPTTP53 | |
| Hydrochloric Acid SCHEMBL9526271 | 0.82 | SLC6A9 (0.38) | ALDH1A1HSD17B10MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9525020 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10MTNR1AMTNR1BMEN1 | |
| SCHEMBL9525126 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MTNR1AMTNR1BMEN1 | |
| Hydrochloric Acid SCHEMBL9524100 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MTNR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |