Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224612 | 0.83 | HPGD (0.40) | DPP4KDM4EALDH1A1HPGDHTR1A | |
| SCHEMBL9525389 | 0.77 | MAP3K14 (0.35) | DPP4KDM4EALDH1A1HPGD | |
| SCHEMBL8593528 | 0.75 | ADRA1D (0.58) | KDM4EALDH1A1HPGDHTR1AADRA1D | |
| SCHEMBL7464571 | 0.75 | ADRA1D (0.58) | KDM4EALDH1A1HPGDHTR1AADRA1D | |
| SCHEMBL7464563 | 0.75 | ADRA1D (0.58) | KDM4EALDH1A1HPGDHTR1AADRA1D | |
| SCHEMBL30705312 | 0.74 | HPGD (0.40) | KDM4EALDH1A1HPGDADRA1DADRA1A | |
| SCHEMBL9481539 | 0.74 | CA2 (0.38) | HPGDADRA1DADRA1AADRA1B | |
| SCHEMBL9526092 | 0.74 | AHR (0.41) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9482152 | 0.74 | CA2 (0.38) | HPGDADRA1DADRA1AADRA1B | |
| SCHEMBL1292099 | 0.72 | POLB (0.45) | KDM4EALDH1A1HPGDHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359290-B1 | AROMATIC DIOLS | GLAXO GROUP LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |