Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530028 | 0.79 | ELANE (0.39) | ELANE | |
| SCHEMBL25601297 | 0.75 | ELANE (0.38) | ELANE | |
| SCHEMBL9526462 | 0.74 | — | — | |
| SCHEMBL8797888 | 0.74 | ELANE (0.30) | ELANE | |
| SCHEMBL25607704 | 0.71 | ELANE (0.41) | ELANE | |
| SCHEMBL22844659 | 0.71 | ELANE (0.41) | ELANE | |
| SCHEMBL7831926 | 0.70 | ELANE (0.40) | ELANE | |
| SCHEMBL8133240 | 0.70 | ELANE (0.40) | ELANE | |
| SCHEMBL10766413 | 0.69 | CASP1 (0.31) | — | |
| SCHEMBL7565158 | 0.69 | ELANE (0.41) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181831-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ACYLOXYAZETIDINONES | CIBA-GEIGY AG (CH) | 1993-08-25 | — | — | EP | disclosed |
| EP-0259268-A1 | Process for the preparation of optically active beta-lactams | CIBA-GEIGY AG (CH) | 1988-03-09 | — | — | EP | disclosed |
| EP-0221846-A1 | Optically active acyloxyazotidinones | CIBA-GEIGY AG (CH) | 1987-05-13 | — | — | EP | disclosed |
| EP-0181831-A2 | Process for the preparation of optically active acyloxyazetidinones | CIBA-GEIGY AG (CH) | 1986-05-21 | — | — | EP | disclosed |