Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791465 | 0.82 | HDAC3 (0.51) | ADRA2CHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL154607 | 0.82 | HPGD (0.53) | ADRA2CHDAC1HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL27871652 | 0.81 | HPGD (0.52) | ADRA2CLPAR1HDAC1HDAC6HDAC3 | |
| SCHEMBL7751510 | 0.79 | ADRA2C (0.69) | ADRA2CHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL4918307 | 0.79 | ADRA2C (0.50) | ADRA2CHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL7543305 | 0.77 | HPGD (0.43) | ADRA2CLPAR1HDAC1HDAC6HDAC3 | |
| SCHEMBL5154776 | 0.77 | ADRA2C (0.55) | ADRA2CKMT2AGAATSHRMEN1 | |
| SCHEMBL8615545 | 0.76 | LIMK2 (0.63) | LPAR1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL10925719 | 0.76 | HPGD (0.56) | HDAC1HDAC6HDAC3HDAC2LTB4R2 | |
| SCHEMBL30957362 | 0.75 | NPC1 (0.57) | ADRA2CHDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |