Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527302 | 0.95 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9527261 | 0.87 | AGTR2 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9530087 | 0.85 | AGTR2 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9530085 | 0.84 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9525641 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9529961 | 0.82 | AGTR2 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9753975 | 0.81 | AGTR2 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9526473 | 0.79 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9526433 | 0.76 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL10304718 | 0.75 | AGTR1 (0.45) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523141-A4 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | — | 1993-04-21 | — | — | EP | claimed |
| EP-0523141-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | claimed |
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | claimed |
| EP-0523141-A4 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0523141-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | disclosed |