Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380267 | 0.77 | HSD17B10 (0.49) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9529307 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9529732 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL2202173 | 0.74 | BCL2L1 (0.54) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9536812 | 0.74 | ALDH1A1 (0.60) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL15661524 | 0.73 | PDE10A (0.42) | KDM4EALDH1A1GAABCL2L1PDE10A | |
| SCHEMBL28946476 | 0.73 | GSK3B (0.59) | KDM4EALDH1A1GAAL3MBTL1BCL2L1 | |
| SCHEMBL30132131 | 0.72 | ALDH1A1 (0.58) | KDM4EALDH1A1GAABCL2L1HSD17B10 | |
| SCHEMBL7365683 | 0.72 | KDM4E (0.51) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11008749 | 0.72 | MCL1 (0.51) | KDM4EALDH1A1GAAGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |