Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008749 | 0.82 | MCL1 (0.51) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9525290 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11736677 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9536812 | 0.77 | ALDH1A1 (0.60) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9219527 | 0.77 | PGR (0.49) | KDM4EGAAMEN1HTTKMT2A | |
| SCHEMBL9701575 | 0.76 | MDM2 (0.59) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11737297 | 0.76 | ERCC1 (0.57) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL7365683 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL2741753 | 0.76 | AHR (0.43) | KDM4EGAAMEN1HTTKMT2A | |
| SCHEMBL9700724 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1GAAGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |