Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.43 |
| ▸ | CA2 | P00918 | 8/20 | 0.43 |
| ▸ | CA4 | P22748 | 8/20 | 0.43 |
| ▸ | CA6 | P23280 | 8/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946264 | 0.76 | CA1 (0.43) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL9531171 | 0.75 | CA1 (0.40) | CA1CA2CA4CA6MEN1 | |
| SCHEMBL9528764 | 0.72 | CA1 (0.53) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL8946893 | 0.72 | CA1 (0.52) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL9531330 | 0.72 | CA1 (0.49) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL8946827 | 0.71 | CA1 (0.48) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL8946637 | 0.68 | CA1 (0.54) | CA1CA2CA4CA6MAPT | |
| SCHEMBL28340252 | 0.67 | KDM4E (0.54) | HIF1AKDM4EMEN1MAPTKMT2A | |
| SCHEMBL23649412 | 0.66 | CA1 (0.47) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL29834173 | 0.66 | CA1 (0.47) | CA1CA2CA4CA6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |