Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA4 | P22748 | 7/20 | 0.43 |
| ▸ | CA6 | P23280 | 7/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.32 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.32 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946827 | 0.79 | CA1 (0.48) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL9531330 | 0.77 | CA1 (0.49) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL9526355 | 0.76 | CA1 (0.43) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL10381644 | 0.70 | CA1 (0.41) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL8946893 | 0.69 | CA1 (0.52) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL9527337 | 0.68 | CA1 (0.44) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL14447191 | 0.67 | CA1 (0.53) | CA1CA2CA4CA6KDR | |
| SCHEMBL9528764 | 0.67 | CA1 (0.53) | CA1CA2CA4CA6HIF1A | |
| SCHEMBL9531171 | 0.65 | CA1 (0.40) | CA1CA2CA4CA6KDR | |
| SCHEMBL9527328 | 0.65 | CA1 (0.50) | CA1CA2CA4CA6KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0481708-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1992-04-22 | — | — | EP | disclosed |