Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.34 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.31 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.31 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10382343 | 0.91 | HIF1A (0.36) | CA1CA2CA4CA6MEN1 | |
| SCHEMBL7200645 | 0.76 | CA1 (0.45) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL9526355 | 0.75 | CA1 (0.43) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL9526921 | 0.74 | CA1 (0.46) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL16559092 | 0.68 | PNMT (0.49) | CA1CA2CA4CA6PGR | |
| SCHEMBL8946637 | 0.65 | CA1 (0.54) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL8946264 | 0.65 | CA1 (0.43) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL9527581 | 0.64 | CA1 (0.46) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL9528300 | 0.64 | DDB1 (0.34) | CA1CA2CA4CA6KDR | |
| SCHEMBL23649412 | 0.64 | CA1 (0.47) | CA1CA2CA4CA6CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |