Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526517 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9524667 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9524661 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9702632 | 0.75 | XDH (0.48) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9702637 | 0.75 | XDH (0.48) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9525815 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9525827 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9526260 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9526250 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9525990 | 0.70 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |