Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702632 | 1.00 | XDH (0.48) | XDHKDM4EALDH1A1GLAGAA | |
| SCHEMBL9701461 | 0.85 | ALDH1A1 (0.47) | XDHKDM4EALDH1A1GLAGAA | |
| SCHEMBL9701458 | 0.85 | ALDH1A1 (0.47) | XDHKDM4EALDH1A1GLAGAA | |
| SCHEMBL7371751 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL7371748 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9701871 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9526507 | 0.75 | KDM4E (0.47) | XDHKDM4EALDH1A1GLAGAA | |
| SCHEMBL9526517 | 0.75 | KDM4E (0.47) | XDHKDM4EALDH1A1GLAGAA | |
| SCHEMBL11174883 | 0.74 | KDM4E (0.53) | XDHKDM4EALDH1A1GLAGAA | |
| SCHEMBL9526574 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1GLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |