Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 8/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710582 | 0.92 | MMP8 (0.79) | MMP8ALDH1A1RECQLPIN1TAAR1 | |
| SCHEMBL27993635 | 0.84 | MMP8 (0.69) | MMP8ALDH1A1RECQLPIN1TAAR1 | |
| SCHEMBL16254170 | 0.84 | MMP8 (0.54) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL12574782 | 0.83 | MMP8 (0.63) | MMP8ALDH1A1RECQLPIN1TAAR1 | |
| SCHEMBL1247153 | 0.83 | MMP8 (0.68) | MMP8ALDH1A1RECQLPIN1TAAR1 | |
| SCHEMBL14498571 | 0.82 | MMP8 (0.51) | MMP8ALDH1A1RECQLNPSR1SMN1; SMN2 | |
| SCHEMBL28817686 | 0.82 | MMP8 (0.66) | MMP8ALDH1A1RECQLPIN1LMNA | |
| SCHEMBL1492859 | 0.81 | MMP8 (0.65) | MMP8ALDH1A1RECQLPIN1TAAR1 | |
| SCHEMBL22850601 | 0.81 | MMP8 (0.53) | MMP8ALDH1A1RECQLLMNASMN1; SMN2 | |
| SCHEMBL17403335 | 0.81 | MMP8 (0.53) | MMP8ALDH1A1RECQLPIN1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011014520-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-02-03 | — | — | WO | disclosed |
| EP-0310745-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | ORION-YHTYMÄ OY (FI) | 1993-01-27 | — | — | EP | disclosed |
| EP-0183492-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1989-11-15 | — | — | EP | disclosed |
| EP-0310745-A2 | Substituted imidazole derivatives and their preparation and use | ORION-YHTYMÄ OY (FI) | 1989-04-12 | — | — | EP | disclosed |
| US-4689339-A | 4-dihydroinden-2-yl-, 4-tetrahydronaphth-2-yl-, and 4-dihydrobenzofuran-2-ylimidazoles, useful to block α2 -adrenergic receptors | FARMOS YHTYMA OY (FI) | 1987-08-25 | — | — | US | disclosed |
| EP-0183492-A1 | Substituted imidazole derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1986-06-04 | — | — | EP | disclosed |