Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710582 | 0.88 | MMP8 (0.79) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL27993635 | 0.87 | MMP8 (0.69) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL9526598 | 0.83 | MMP8 (0.73) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL12913254 | 0.80 | MMP8 (0.60) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL28817686 | 0.78 | MMP8 (0.66) | MMP8ALDH1A1RECQLPIN1LMNA | |
| SCHEMBL29277123 | 0.78 | ALDH1A1 (0.60) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL1492859 | 0.78 | MMP8 (0.65) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL7362869 | 0.76 | MMP8 (0.59) | MMP8ALDH1A1RECQLPIN1LMNA | |
| SCHEMBL10821760 | 0.76 | MMP8 (0.63) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL12574782 | 0.76 | MMP8 (0.63) | MMP8ALDH1A1RECQLPIN1PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011014520-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-02-03 | — | — | WO | disclosed |