Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131729 | 0.88 | ACHE (0.39) | ALDH1A1CYP3A4 | |
| SCHEMBL1841249 | 0.86 | ALDH1A1 (0.36) | ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL19790062 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL19790037 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CYP3A4 | |
| SCHEMBL1838114 | 0.79 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL1837556 | 0.79 | SMN1; SMN2 (0.36) | ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL13852751 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP3A4 | |
| SCHEMBL1838842 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL1841614 | 0.76 | KCNJ1 (0.33) | ALDH1A1CYP3A4 | |
| SCHEMBL19795030 | 0.76 | ALDH1A1 (0.33) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185493-B1 | IMIDAZOLINONE-CONTAINING POLYMERS AND COPOLYMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| US-4785070-A | THERMAL CYCLODEHYDRATION OF AN AZLACTONE OR 4,4-DISUBSTITUTED 2-OXAZOLIN-5-ONE AND DIAMINE; WATER SOLUBILITY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| EP-0185493-A2 | Imidazolinone-containing polymers and copolymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-06-25 | — | — | EP | disclosed |