SCHEMBL9527147

SCHEMBL9527147

Cc1nnc(C(Cl)C(=O)C(=O)S)s1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9527140 0.72
SCHEMBL11147985 0.69
SCHEMBL11331982 0.68
SCHEMBL11344359 0.67 L3MBTL1 (0.33) GAAL3MBTL1TP53POLBSMN1; SMN2
SCHEMBL20204368 0.63
SCHEMBL20204366 0.63
SCHEMBL16797589 0.63 LMNA (0.43) GAAL3MBTL1TP53POLBSMN1; SMN2
SCHEMBL17824102 0.63 P2RX3 (0.38) GAAL3MBTL1TP53POLBSMN1; SMN2
SCHEMBL1106957 0.62
SCHEMBL7023863 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0153229-B1 1-DETHIA 2-THIA-CEPHALOSPORANIC ACID DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND THE COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1993-04-07 EP disclosed