Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527786 | 0.85 | AGTR2 (0.47) | AGTR2AGTR1 | |
| SCHEMBL9531915 | 0.80 | AGTR2 (0.46) | AGTR2AGTR1 | |
| SCHEMBL9526726 | 0.79 | AGTR1 (0.50) | AGTR2AGTR1 | |
| SCHEMBL9527464 | 0.73 | — | — | |
| SCHEMBL9526081 | 0.70 | AGTR2 (0.53) | AGTR2AGTR1 | |
| SCHEMBL9527261 | 0.70 | AGTR2 (0.53) | AGTR2AGTR1 | |
| SCHEMBL3264923 | 0.69 | AGTR2 (0.44) | AGTR2AGTR1 | |
| SCHEMBL9525641 | 0.68 | AGTR1 (0.49) | AGTR2AGTR1 | |
| SCHEMBL9754267 | 0.68 | — | — | |
| SCHEMBL9526953 | 0.68 | AGTR2 (0.47) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523141-A4 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | — | 1993-04-21 | — | — | EP | claimed |
| EP-0523141-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | claimed |
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | claimed |
| EP-0523141-A4 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0523141-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | disclosed |