Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528536 | 0.89 | KMT2A (0.36) | KMT2ACYP2C9CYP3A4CYP2E1CYP2A6 | |
| SCHEMBL9528114 | 0.87 | CYP2C9 (0.39) | KMT2ACYP2C9CYP3A4LMNAADRA1D | |
| SCHEMBL9532085 | 0.81 | CYP11B1 (0.45) | KMT2ACYP2C9LMNAMEN1CYP1A2 | |
| SCHEMBL10406923 | 0.78 | CYP1A2 (0.40) | KMT2ACYP2A6LMNACYP1A2CYP2D6 | |
| SCHEMBL9527768 | 0.78 | CYP2C9 (0.40) | KMT2ACYP2C9LMNAMEN1CYP1A2 | |
| SCHEMBL9529668 | 0.77 | KDM4E (0.47) | KMT2ACYP2C9CYP3A4LMNAADRA1D | |
| SCHEMBL9527691 | 0.77 | TSHR (0.45) | KMT2ACYP2C9CYP3A4LMNAMEN1 | |
| SCHEMBL9528361 | 0.74 | ALDH1A1 (0.50) | KMT2ACYP2A6LMNAMEN1CYP1A2 | |
| SCHEMBL9528579 | 0.74 | ALDH1A1 (0.53) | KMT2ALMNAMEN1ALDH1A1MAPK1 | |
| SCHEMBL9528051 | 0.74 | ALDH1A1 (0.40) | KMT2ACYP2C9CYP3A4CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |