Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527691 | 0.90 | TSHR (0.45) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL9528579 | 0.88 | ALDH1A1 (0.53) | TSHRLMNAKMT2ATDP1PLOD2 | |
| SCHEMBL9527614 | 0.85 | EPHX2 (0.48) | LMNAKMT2ATDP1PLOD2MEN1 | |
| SCHEMBL9527670 | 0.85 | EPHX2 (0.48) | LMNAKMT2ATDP1MEN1NPC1 | |
| SCHEMBL9528361 | 0.85 | ALDH1A1 (0.50) | TSHRLMNAKMT2ATDP1MEN1 | |
| SCHEMBL9532120 | 0.84 | EPHX2 (0.47) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL10407004 | 0.84 | TSHR (0.43) | TSHRKMT2APLOD2RAB9ASMN1; SMN2 | |
| SCHEMBL10406923 | 0.83 | CYP1A2 (0.40) | LMNAKMT2APLOD2SMN1; SMN2GAA | |
| SCHEMBL9529668 | 0.82 | KDM4E (0.47) | LMNAKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL9529147 | 0.81 | NOTUM (0.44) | LMNAKMT2APLOD2MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |