Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529948 | 0.90 | GAA (0.47) | KDM4EGAAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL10407326 | 0.86 | CYP2C19 (0.47) | KDM4EMAPTALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL9532085 | 0.82 | CYP11B1 (0.45) | KDM4EGAAALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL10406923 | 0.79 | CYP1A2 (0.40) | KDM4EGAAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9527691 | 0.78 | TSHR (0.45) | KDM4EGAAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9529276 | 0.77 | ALDH1A1 (0.46) | KDM4EMAPTALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL9527237 | 0.77 | KMT2A (0.37) | KDM4EALDH1A1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL9528361 | 0.75 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL9528579 | 0.75 | ALDH1A1 (0.53) | KDM4EGAAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9529147 | 0.74 | NOTUM (0.44) | GAAMAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |