Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 4/20 | 0.32 |
| ▸ | CBFB | Q13951 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527817 | 0.89 | ATP4A (0.36) | RUNX1CBFB | |
| SCHEMBL9529518 | 0.87 | ATP4A (0.35) | S1PR2RUNX1CBFB | |
| SCHEMBL9531496 | 0.85 | ATP4A (0.42) | S1PR2RUNX1CACNA1H | |
| SCHEMBL9527334 | 0.83 | CBFB (0.40) | TRPV1RUNX1CBFB | |
| SCHEMBL9531500 | 0.81 | ATP4A (0.44) | CBFB | |
| SCHEMBL10713063 | 0.80 | KIF11 (0.39) | TRPV1CBFB | |
| SCHEMBL10713068 | 0.80 | DYRK1A (0.46) | TRPV1CBFB | |
| SCHEMBL9526251 | 0.79 | ATP4A (0.38) | TRPV1 | |
| SCHEMBL9526628 | 0.79 | CYP1A2 (0.48) | — | |
| SCHEMBL9527662 | 0.78 | RUNX1 (0.33) | RUNX1CBFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134400-B1 | FLUOROALKOXYSUBSTITUTED PYRIDYLMETHYLTHIO-(OR SULFINYL-)BENZIMIDAZOLES HAVING A SECRETOLYTIC ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4555518-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-11-26 | — | — | US | disclosed |
| EP-0134400-A2 | Fluoroalkoxysubstituted pyridylmethylthio-(or sulfinyl-)benzimidazoles having a secretolytic activity | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |