Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13767995 | 0.82 | THRB (0.33) | ALDH1A1LMNA | |
| SCHEMBL9701518 | 0.78 | TDP1 (0.36) | ALDH1A1LMNATDP1 | |
| SCHEMBL8940598 | 0.77 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL175826 | 0.76 | — | — | |
| SCHEMBL9106 | 0.75 | — | — | |
| SCHEMBL3731262 | 0.75 | — | — | |
| SCHEMBL22907221 | 0.75 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL28156275 | 0.73 | — | — | |
| SCHEMBL27647831 | 0.73 | — | — | |
| SCHEMBL27668270 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573455-A1 | METHOD OF PREPARATION OF PILOCARPINES AND INTERMEDIATES THEREOF | MACFARLAN SMITH LIMITED (GB) | 1993-12-15 | — | — | EP | claimed |
| WO-1992014693-A1 | METHOD OF PREPARATION OF PILOCARPINES AND INTERMEDIATES THEREOF | MACFARLAN SMITH LIMITED (GB) | 1992-09-03 | — | — | WO | claimed |
| EP-0573455-A1 | METHOD OF PREPARATION OF PILOCARPINES AND INTERMEDIATES THEREOF | MACFARLAN SMITH LIMITED (GB) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992014693-A1 | METHOD OF PREPARATION OF PILOCARPINES AND INTERMEDIATES THEREOF | MACFARLAN SMITH LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |
| EP-0165289-B1 | NOVEL DERIVATIVES OF GUANINE | Medivir Aktiebolag (SE) | 1989-04-05 | — | — | EP | disclosed |
| US-4798833-A | VIRICIDES | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1989-01-17 | — | — | US | disclosed |
| EP-0165289-A1 | NOVEL DERIVATIVES OF GUANINE. | ASTRA LAEKEMEDEL AB (SE) | 1985-12-27 | — | — | EP | disclosed |
| WO-1985002845-A1 | NOVEL DERIVATIVES OF GUANINE | Astra Läkemedel Aktiebolag (SE) | 1985-07-04 | — | — | WO | disclosed |
| EP-0146516-A2 | Derivatives of Guanine, process for their preparation and a pharmaceutical preparation | Astra Läkemedel Aktiebolag (SE) | 1985-06-26 | — | — | EP | disclosed |